Not to be confused with. Immune thrombocytopenia Synonyms immune thrombocytopenic purpura, idiopathic thrombocytopenic purpura, idiopathic immune thrombocytopenia, primary immune thrombocytopenia, idiopathic thrombocytopenic purpura, primary immune thrombocytopenic purpura, autoimmune thrombocytopenic purpura Petechiae, or small bruise-like markings, may occur in ITP Immune thrombocytopenia ( ITP) is a type of defined as isolated low count () with normal and the absence of other causes of thrombocytopenia. It causes a characteristic rash and an increased tendency to bleed. Two distinct clinical syndromes manifest as an acute condition in children and a chronic condition in adults. The acute form often follows an infection and has a spontaneous resolution within two months. Chronic immune thrombocytopenia persists longer than six months with a specific cause being unknown. ITP is an disease with detectable against several platelet surface. Immune thrombocytopenic purpura (ITP) is a bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting. People with the disease have too few platelets in the blood. Read about idiopathic thrombocytopenic purpura (ITP) symptoms like red spots on the skin, purplish bruising, nosebleeds, bleeding gums, blood in the urine or stool, fatigue, and low platelet count. ITP is diagnosed by a low platelet count in a (a common ). However, since the diagnosis depends on the exclusion of other causes of a low platelet count, additional investigations (such as a ) may be necessary in some cases. In mild cases, only careful observation may be required but very low counts or significant bleeding may prompt treatment with,,, or immunosuppressive medications. Refractory ITP (not responsive to conventional treatment) may require, the surgical removal of the spleen. May be used in severe bleeding together with a very low count. Sometimes the body may compensate by making abnormally large platelets. Contents • • • • • • • • • • • • • • • • • • Signs and symptoms [ ] Signs include the spontaneous formation of (purpura) and (tiny bruises), especially on the, and/or, and (excessive ), any of which may occur if the platelet count is below 20,000 per μl.
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